We use automated low-cost sequencing to detect transmission in your hospital.
Infection prevention teams work hard to identify and control outbreaks, but traditional infection control methods have been recently shown to miss much of the transmission. Without genomic sequencing, it's difficult to detect outbreaks, or to track how pathogens spread within and between facilities, leading to delayed responses and missed opportunities to contain transmission, and most importantly, extended patient stays and adverse outcomes. Whole genome sequencing provides a complete view of pathogen transmission, enabling IP teams to identify sources of infection, and implement targeted interventions. NGD makes this powerful technology accessible by automating sequencing and bioinformatics, reducing cost, hands-on time, and the need for specialized expertise—empowering hospitals to catch spread of infection, guide IP teams to prevent further transmission, and thereby reduce the costly extension of stays that it causes.
The Challenge: Preventing Healthcare-Associated Infections
Hospital-acquired infections pose a major challenge to patient safety and operational efficiency. Infection prevention teams are charged with:
detecting transmission between patients, caregivers and equipment
identifying the root causes of transmission and developing interventions to rapidly quench them
We harness the power of WGS to detect transmission and prevent outbreaks.
We provide an end-to-end highly automated service, complete with equipment and consumables, on-site in your own lab, to give you actionable results within 24 hours.
Our customers obtain:
Rapid Transmission Detection
We use prospective sequencing to identify transmission in 24 hours instead of weeks
Advanced Analytics
Track infection trends across facilities with real-time analytics and automated epidemiology
Identify outbreak patterns and respond proactively
Automation used to be the bottleneck for adopting sequencing in hospitals—NGD has assembled the technologies that now enable seamless, low-cost sequencing with minimal hands-on time and no need for specialized expertise, from sequencing through bioinformatics.
How our system can benefit you:
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Get everything from sample prep to bioinformatic results for as little as $75 per sample.
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Identify transmission patterns in just one day.
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Our equipment and pioneering interface caters to all users; it can be used by infection control teams, not just domain experts.
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On-site installation and training included, with no prior skill required.
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Process 24-48 samples at once, maximizing lab efficiency.
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Technicians need only prepare standard isolate dilutions and lay out reagents.
Timeline of Our 24-Hour Turnaround: Sample to Sequencing and Analysis
Advanced analytics at your fingertips
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Transmission Detection Module
This module highlights new transmission chains, based on recursively computed SNP-level difference between genomes. New candidate transmission clusters are presented in a form designed to guide action by infection control to validate and if appropriate take steps to intervene to promptly curtail outbreak as it begins.
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Antibiogram Prediction Module
Sequence-based predictions of susceptible (S) and resistant (R) for all relevant drugs are furnished. Resistance calls are given along with the genomic element (either resistance gene or genes, or resistance associated mutations) that prompted the predicted R phenotype. Phenotypic antibiogram data can be imported for comparison.
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Cohort Analysis
Enables users to seamlessly and interactively visualize relatedness of tens of thousands of samples in a phylogenetic tree next to other properties of the samples such as their phenotype (e.g. resistance or susceptibility), presence and absence of genes, alleles and their copy number as well as correlation between them.
Low Cost. Low Hands On Time. Low Skill. Overnight Sample-to-Results.
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Get everything from sample prep to bioinformatic results for as little as $75 per sample.
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We provide more than just the hardware; we’ll deliver everything you need to get going.
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Our team will install our system in your lab, and provide you with training and reference materials. In addition, our customer service team are here if you have any further questions.
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Includes our NGD Dashboard.
Take your productivity one step further and benefit from analytics, available to you automatically the day after sequencing.
Industry Testimonials
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“Next Gen Diagnostics’ system was put in place at Addenbrooke’s between 2018-2019, and helped both catch transmission and curtail outbreaks, [...] sparing patients. We believe this is the future of infection control.”
Spokesperson
Addenbrooke’s Hospital, Cambridge UK
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“It is increasingly clear that WGS is going to be central to clinical infectious disease practice as well as to hospital infection prevention, and NGD is one of the leaders of this transformation.”
Dr. Linoj Samuel
Division Head of the Clinical Microbiology Laboratory for Henry Ford Health, Michigan
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“We know that utilization of the unsurpassable depth of information available in WGS is increasingly the future of microbiology diagnostics and infection control, and we look forward to this timely and compelling opportunity to work with NGD.”
Dr. Sharon Amit
Medical Director of Clinical Microbiology Laboratory at Sheba